Ethyl Imidazole-1-carboxylate (EImC) as a Carbonylating Agent

Various substituted oxazolidin-2-ones were synthesized from the corresponding amino alcohols using ethyl imidazole-1-carboxylate (EImC). Highly substituted and sterically hindered amino alcohols and amino alcohols having a free hydroxy group were cyclized to oxazolidin-2-ones efficiently. This metho...

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Bibliographic Details
Published in:Chemistry letters 2013-02, Vol.42 (2), p.109-109
Main Authors: Veeraswamy, S, Indrasena Reddy, K, Venkat Ragavan, R, Yennam, Satyanarayana, Jayashree, A
Format: Article
Language:English
Subjects:
Alcohols
Carbonyls
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Summary:Various substituted oxazolidin-2-ones were synthesized from the corresponding amino alcohols using ethyl imidazole-1-carboxylate (EImC). Highly substituted and sterically hindered amino alcohols and amino alcohols having a free hydroxy group were cyclized to oxazolidin-2-ones efficiently. This method is simple and produces oxazolidin-2-ones in very good yield.
ISSN:0366-7022
1348-0715