Melicodenines A and B, novel Diels–Alder type adducts isolated from Melicope denhamii

Two novel Diels–Alder type adducts, melicodenines A ( 1) and B ( 2), were isolated from the leaves of Melicope denhamii (Seem.) T. G. Hartley and their structures were established by spectroscopic analyses, including extensive 2D NMR experiments. Compound 1 is a bisquinolinone alkaloid comprised of...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2011-09, Vol.52 (36), p.4694-4696
Main Authors: Nakashima, Ken-ichi, Oyama, Masayoshi, Ito, Tetsuro, Witono, Joko Ridho, Darnaedi, Dedy, Tanaka, Toshiyuki, Murata, Jin, Iinuma, Munekazu
Format: Article
Language:English
Subjects:
Adducts
Alkaloids
Chemistry
Conjugates
Diels–Alder cycloaddition
Ethers
Exact sciences and technology
Heterocyclic compounds
Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms
Heterocyclic compounds with only one n hetero atom and condensed derivatives
Melicope denhamii
Nuclear magnetic resonance
Organic chemistry
Preparations and properties
Quinolinone
Rutaceae
Spectroscopic analysis
Tetrahedrons
Two dimensional
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Two novel Diels–Alder type adducts, melicodenines A ( 1) and B ( 2), were isolated from the leaves of Melicope denhamii (Seem.) T. G. Hartley and their structures were established by spectroscopic analyses, including extensive 2D NMR experiments. Compound 1 is a bisquinolinone alkaloid comprised of two N-methylflindersines ( 3), while compound 2 is the first naturally occurring quinolinone–acetophenone conjugate composed of 3 and an evodionol methyl ether ( 4).
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2011.07.013