An efficient solvent free multicomponent synthesis of functionalized 4H-chromenes by using reusable, heterogeneous Amberlite IRA-400 Cl resin as catalyst

[Display omitted] A simple and efficient Amberlite IRA-400 Cl resin catalyzed multicomponent reaction of 2-hydroxy-1-naphthaldehyde, 1,3-diketone, and nucleophile under solvent free condition to obtain the biological important 4H-chromene derivatives has been outlined. Significant features of this m...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2015-01, Vol.56 (1), p.150-154
Main Authors: Harichandran, Gurusamy, Parameswari, Parkunan, Kanagaraj, Madasamy, Shanmugam, Ponnusamy
Format: Article
Language:English
Subjects:
4H-chromene
Accessibility
Amberlite (trademark)
Amberlite IRA-400 Cl resin
Catalysts
Cost effectiveness
Derivatives
Michael reaction
Multicomponent reactions
Polymers
Resins
Solvent free condition
Solvents
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[Display omitted] A simple and efficient Amberlite IRA-400 Cl resin catalyzed multicomponent reaction of 2-hydroxy-1-naphthaldehyde, 1,3-diketone, and nucleophile under solvent free condition to obtain the biological important 4H-chromene derivatives has been outlined. Significant features of this method are the simplicity of the procedure, the ready accessibility, and cost effectiveness of the catalyst, and higher yields in a relatively short reaction time. Structures of compounds 4j and 5c were confirmed from single crystal X-ray studies.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2014.11.043