Frontispiece: Reversal of a Single Base-Pair Step Controls Guanine Photo-Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex

DNA Photooxidation Small changes in DNA sequence can have major biological effects. P. M. Keane, C. J. Cardin, J. M. Kelly et al. show on page 8364 ff. that the reversal of a single base‐pair step has a dramatic effect on the guanine photooxidation by a DNA‐intercalating RuII complex....

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2015-07, Vol.54 (29), p.np-n/a
Main Authors: Keane, Páraic M., Poynton, Fergus E., Hall, James P., Sazanovich, Igor V., Towrie, Michael, Gunnlaugsson, Thorfinnur, Quinn, Susan J., Cardin, Christine J., Kelly, John M.
Format: Article
Language:English
Subjects:
Biological effects
Control equipment
Deoxyribonucleic acid
DNA
electron transfer
Gene sequencing
Guanines
Photooxidation
ruthenium
time-resolved spectroscopy
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Summary:DNA Photooxidation Small changes in DNA sequence can have major biological effects. P. M. Keane, C. J. Cardin, J. M. Kelly et al. show on page 8364 ff. that the reversal of a single base‐pair step has a dramatic effect on the guanine photooxidation by a DNA‐intercalating RuII complex.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201582961