Nanoscopy with Focused Light (Nobel Lecture)

A picture is worth a thousand words—This doesn't only apply to everyday life but also to the natural sciences. It is, therefore, probably not by chance that the historical beginning of modern natural sciences very much coincides with the invention of light microscopy. S. W. Hell shows in his No...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2015-07, Vol.54 (28), p.8054-8066
Main Author: Hell, Stefan W.
Format: Article
Language:English
Subjects:
Barriers
Diffraction
diffraction limit
Historic
Inventions
Lectures
Microscopy
Microscopy, Electron, Transmission - methods
Microscopy, Fluorescence - methods
nanoscopy
Nanostructure
Nanotechnology - methods
Pictures
STED microscopy
super-resolution
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Summary:A picture is worth a thousand words—This doesn't only apply to everyday life but also to the natural sciences. It is, therefore, probably not by chance that the historical beginning of modern natural sciences very much coincides with the invention of light microscopy. S. W. Hell shows in his Nobel Lecture that the diffraction resolution barrier has been overcome by using molecular state transitions (e.g. on/off) to make nearby molecules transiently discernible.
ISSN:1433-7851
1521-3773
1521-3773
DOI:10.1002/anie.201504181