Trifluoroacetic anhydride-catalyzed conjugate addition of boronic acids to [alpha],[beta]-unsaturated ketones

The conjugate addition of boronic acids to [alpha],[beta]-unsaturated ketones catalyzed by acylating reagents has been explored. The results show that trifluoroacetic anhydride catalyzes the addition of vinylboronic acids under experimentally simple and metal-free conditions for a variety of substra...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2012-08, Vol.53 (35), p.4721-4724
Main Authors: Roscales, Silvia, Rincon, Angela, Buxaderas, Eduardo, Csakye, Aurelio G
Format: Article
Language:English
Subjects:
Anhydrides
Conjugates
Ketones
Tetrahedrons
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The conjugate addition of boronic acids to [alpha],[beta]-unsaturated ketones catalyzed by acylating reagents has been explored. The results show that trifluoroacetic anhydride catalyzes the addition of vinylboronic acids under experimentally simple and metal-free conditions for a variety of substrates with good yields.
ISSN:0040-4039
DOI:10.1016/j.tetlet.2012.06.105