Simultaneous dehalogenation and hydrogenation reduction of halogen-heteroaromatic aldehydes

Treatment of halogen-heteroaromatic aldehydes with catalytic amount of PdCl2 under atmosphere pressure of hydrogen in base medium (sodium acetate) leads to the corresponding dehalogenated primary alcohols. The reaction system was especially effective for the heteroaromatic compounds bearing aldehyde...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2012-07, Vol.53 (29), p.3798-3801
Main Authors: Chen, Xi-Bo, Hu, Qiu-Peng, Yuan, Qian-Jia, Ding, Wei, Ren, Jiangmeng, Zeng, Bu-Bing
Format: Article
Language:English
Subjects:
Aldehydes
Barometric pressure
Bearing
Catalysis
Dehalogenation
Halides
Halogen-heteroaromatic aldehydes
Heteroaromatic compounds
Hydrogen
Hydrogenation
Palladium catalysts
Tetrahedrons
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Treatment of halogen-heteroaromatic aldehydes with catalytic amount of PdCl2 under atmosphere pressure of hydrogen in base medium (sodium acetate) leads to the corresponding dehalogenated primary alcohols. The reaction system was especially effective for the heteroaromatic compounds bearing aldehyde groups and halides (bromo- or chloro-functions).
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2012.05.054