Simultaneous Determination of 18 Photoinitiators Residues in Paper-made Packaging by Gas Chromatograph-Mass Spectrometry after Dispersive Solid Phase Extraction Cleanup

• Published in: Fēnxī huàxué 2013-01, Vol.41 (9), p.1334-1340
• Main Authors: LI, Zhong-Hao, FAN, Zi-Yan, BIAN, Zhao-Yang, WANG, Qing-Hua, FAN, Duo-Qing, LIU, Nan, CHEN, Zai-Gen, TANG, Gang-Ling
• Format: Article
• Language: English
• Subjects: Cleaning; Liquid-liquid extraction; Packaging; Residues; Solid phases; Sorbents; Spectrometry; Spectroscopy
• ISSN: 0253-3820
• DOI: 10.3724/SP.J.1096.2013.30086

A method was developed for the simultaneous determination of 18 photoinitiators (PIs) residues in paper-made packaging by gas chromatograph-mass spectrometry (GC-MS) after dispersive solid phase extraction (d-SPE) cleanup. PIs were ultrasonically extracted by acetonitrile from water presoaked sample, followed by liquid-liquid distribution extraction with n-hexane-acetic ether (3:7, V/V) and cleaned up by the mixed sorbents of anhydrous MgSO sub(4) plus primary secondary amine (PSA) and octadecylsilane (C sub(18)) sorbent power. The ultimate solution was detected and quantified by GC-MS under selected ion monitoring mode by using anthracene D10 as the internal standard. All of the 18 PIs had good linear relationship (R super(2)> 0.997) in the concentrations of 0.01 to 0.2 mg/L. The recoveries of 18 PIs were in the range from 81.6% to 123.8% at three spike levels of 0.1, 0.4 and 2 mg/m super(2) with relative standard deviation (RSD) less than 9.6%. The detection limits of target compounds in the method were ranged from 0.007 mg/m super(2) to 0.023 mg/m super(2). The real sample analysis showed that this simple and accurate method could be used for the determination of the residues of 18 PIs simultaneously in the paper-made packaging sample.