A N-heterocyclic carbene (NHC) platinum complex as pre-catalyst for the intramolecular hydroamination of olefins with secondary alkylamines and oxidative amination of ω-alkenic amines

• Published in: Tetrahedron 2012-04, Vol.68 (15), p.3172-3178
• Main Authors: Zhang, Rui, Xu, Qin, Mei, Liang-yong, Li, Sheng-ke, Shi, Min
• Format: Article
• Language: English
• Subjects: Alkylamines; Amines; Carbenes; Catalysis; Catalysts: preparations and properties; Chemistry; Exact sciences and technology; General and physical chemistry; Heterocyclic compounds; Heterocyclic compounds with only one n hetero atom and condensed derivatives; Intramolecular hydroamination; Kinetics and mechanisms; N-Heterocyclic carbene; Olefins; Organic chemistry; Platinum; Platinum complex; Preparations and properties; Reaction mechanisms; Reactivity and mechanisms; Tetrahedrons; Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry
• ISSN: 0040-4020; 1464-5416
• DOI: 10.1016/j.tet.2012.02.060

A N-heterocyclic carbene (NHC) platinum complex 3 prepared from BINAM was found to be a highly effective pre-catalyst for the intramolecular hydroamination of olefins with secondary alkylamines to give the corresponding intramolecular hydroamination products in excellent yields. The substrate scope has been carefully examined and the plausible reaction mechanism has been also proposed. [Display omitted] A N-heterocyclic carbene (NHC) platinum complex 3 prepared from BINAM was found to be a highly effective pre-catalyst for the intramolecular hydroamination of olefins with secondary alkylamines to give the corresponding intramolecular hydroamination products in excellent yields.