Secondary metabolites from the endophytic fungus Pestalotiopsis virgatula isolated from the mangrove plant Sonneratia caseolaris

Chromatographic analysis of an ethyl acetate extract of Pestalotiopsis virgatula rice cultures yielded four new α-pyrone derivatives, pestalotiopyrones I–L, and the new (6S,1′S,2′S)-hydroxypestalotin, in addition to three known compounds. The planar structures of the new compounds were elucidated on...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2013-06, Vol.54 (25), p.3256-3259
Main Authors: Rönsberg, David, Debbab, Abdessamad, Mándi, Attila, Wray, Victor, Dai, Haofu, Kurtán, Tibor, Proksch, Peter, Aly, Amal H.
Format: Article
Language:English
Subjects:
Constants
Culture
Derivatives
Endophytic fungi
Joining
Mathematical analysis
Oryza sativa
Pestalotiopsis
Pestalotiopsis virgatula
Planar structures
Sonneratia caseolaris
Spectroscopy
Tetrahedrons
α-Pyrones
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Chromatographic analysis of an ethyl acetate extract of Pestalotiopsis virgatula rice cultures yielded four new α-pyrone derivatives, pestalotiopyrones I–L, and the new (6S,1′S,2′S)-hydroxypestalotin, in addition to three known compounds. The planar structures of the new compounds were elucidated on the basis of extensive NMR spectroscopic and mass spectrometric analyses. The absolute configurations of the new compounds were determined on the basis of biosynthetic considerations, coupling constants, and for pestalotiopyrone L by TDDFT ECD calculations of solution conformers.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2013.04.031