p-tert-Butylcalix[8]arene catalysed synthesis of 3,5-dinitrothiophene scaffolds: antiproliferative effect of some representative compounds on selective anticancer cell lines

A new efficient protocol for the synthesis of 3,5-dinitrothiophene scaffolds was developed by using simple p-tert-butylcalix[8]arene in aqueous medium. Biological activities of some representative compounds were also studied to inhibit the cell growth on selective anticancer cell lines.

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Bibliographic Details
Published in:Tetrahedron letters 2014-01, Vol.55 (5), p.996-1001
Main Authors: Sarkar, Piyali, Maiti, Samares, Ghosh, Krishnendu, (Bandyopadhyay), Sumita Sengupta, Butcher, Ray J., Mukhopadhyay, Chhanda
Format: Article
Language:English
Subjects:
3,5-Dinitrothiophene scaffolds
Antiproliferative effect
Antiproliferatives
Aqueous medium
Biological
Biotechnology
Chromatography free
p-Tertbutylcalixarene
Scaffolds
Synthesis (chemistry)
Tetrahedrons
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Description
Summary:A new efficient protocol for the synthesis of 3,5-dinitrothiophene scaffolds was developed by using simple p-tert-butylcalix[8]arene in aqueous medium. Biological activities of some representative compounds were also studied to inhibit the cell growth on selective anticancer cell lines.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2013.12.068