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Facile functionalization at the C2 position of a highly substituted benzofuran
To expedite an SAR study of the C2 position of a highly substituted benzofuran ring system, we developed a method for the preparation of a key precursor, iodide 10. From iodide 10, a diverse set of compounds with different substituents at the C2 position were prepared efficiently.
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Published in: | Tetrahedron letters 2014-04, Vol.55 (14), p.2212-2216 |
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container_end_page | 2216 |
container_issue | 14 |
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container_title | Tetrahedron letters |
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creator | He, Shuwen Li, Peng Dai, Xing McComas, Casey C. Du, Chunyan Wang, Ping Lai, Zhong Liu, Hong Yin, Jingjun Bulger, Paul G. Dang, Qun Xiao, Dong Zorn, Nicolas Peng, Xuanjia Nargund, Ravi P. Palani, Anandan |
description | To expedite an SAR study of the C2 position of a highly substituted benzofuran ring system, we developed a method for the preparation of a key precursor, iodide 10. From iodide 10, a diverse set of compounds with different substituents at the C2 position were prepared efficiently. |
doi_str_mv | 10.1016/j.tetlet.2014.02.051 |
format | article |
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issn | 0040-4039 1873-3581 |
language | eng |
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source | ScienceDirect Journals |
subjects | Benzofuran Iodides Precursors Substituted 2-iodobenzofuran Substituted benzofuran-2-ylboronic acid Suzuki coupling Tetrahedrons |
title | Facile functionalization at the C2 position of a highly substituted benzofuran |
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