Total synthesis of lansiumamides A and B and alatamide

The total syntheses of lansiumamide A, lansiumamide B and alatamide have been completed taking advantage of the dihalo-olefination of N-formylimides. The syntheses are convergent, flexible and allow for the generation of analogues not accessible through other routes.

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Bibliographic Details
Published in:Tetrahedron letters 2014-10, Vol.55 (44), p.6042-6043
Main Authors: Pasqua, Adele E., Ferrari, Frank D., Crawford, James J., Marquez, Rodolfo
Format: Article
Language:English
Subjects:
Accessibility
Alatamide
Lansiumamide
N-Formylimide
Synthesis (chemistry)
Tetrahedrons
Total synthesis
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Description
Summary:The total syntheses of lansiumamide A, lansiumamide B and alatamide have been completed taking advantage of the dihalo-olefination of N-formylimides. The syntheses are convergent, flexible and allow for the generation of analogues not accessible through other routes.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2014.09.008