Synthesis and Characterization of Rare Earth Fluorescent Compound for Biomolecules-labeling

In order to obtain solid phase time-resolved fluorescence immunoassay chelate of new type, 4,4'-di (p-aminophenylethynyl) -6,6'-bis(N,N-bis(ethoxycarbonylmethyl) amino methyl)-2,2'-bipyridine and 4,4'-di(p-aminophenylethynyl) -6,6'-bis(N,N-bis( t-butoxycarbonyl-methyl) amino...

Full description

Saved in:
Bibliographic Details
Published in:Fēnxī huàxué 2013-01, Vol.41 (11), p.1749-1753
Main Authors: XIE, Wen-Bing, CHANG, Yu, ZHANG, Yong-Li, ZHOU, Shi-Hong, WANG, Jin-Long, PAN, Li-Hua
Format: Article
Language:chi ; eng
Subjects:
Chemical compounds
Differential scanning calorimetry
Fluorescence
Immunoassay
Infrared spectroscopy
Rare earth compounds
Rare earth metals
Trifluoroacetates
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In order to obtain solid phase time-resolved fluorescence immunoassay chelate of new type, 4,4'-di (p-aminophenylethynyl) -6,6'-bis(N,N-bis(ethoxycarbonylmethyl) amino methyl)-2,2'-bipyridine and 4,4'-di(p-aminophenylethynyl) -6,6'-bis(N,N-bis( t-butoxycarbonyl-methyl) amino methyl)-2,2'-bipyridine were synthesized from 4, 4'-dinitro-2, 2'-bipyridine-6, 6'-dimethyl bis (trifluoroacetate) by four steps; hydrolyzation, bromination, esterification and substitution. The structures of the compounds were charactered by differential scanning calorimetry, infrared spectroscopy, super(1)H NMR and high resolution mass spectrometry. The properties and functions of the compounds were studied and compared.
ISSN:0253-3820
DOI:10.3724/SP.J.1096.2013.20979