An efficient copper mediated synthetic methodology for benzo[d]isothiazol-3(2H)-ones and related sulfur–nitrogen heterocycles

A copper mediated sulfur–nitrogen coupling reaction for the synthesis of benzo[d]isothiazol-3(2H)-ones and related sulfur–nitrogen heterocycles has been presented, which requires 2-halo-arylamides, sulfur powder, 25–50mol% of copper iodide/1,10-phenanthroline, and potassium carbonate as base.

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Bibliographic Details
Published in:Tetrahedron letters 2012-03, Vol.53 (11), p.1354-1357
Main Authors: Bhakuni, Bhagat Singh, Balkrishna, Shah Jaimin, Kumar, Amit, Kumar, Sangit
Format: Article
Language:English
Subjects:
Benzo[d]isothiazol-3(2H)-ones
Carbon–sulfur bond formation
Chemical reactions
Copper
Copper catalysis
Iodides
Methodology
Potassium carbonate
Sulfur
Synthesis (chemistry)
Tetrahedrons
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Description
Summary:A copper mediated sulfur–nitrogen coupling reaction for the synthesis of benzo[d]isothiazol-3(2H)-ones and related sulfur–nitrogen heterocycles has been presented, which requires 2-halo-arylamides, sulfur powder, 25–50mol% of copper iodide/1,10-phenanthroline, and potassium carbonate as base.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2012.01.003