The synthesis and evaluation of unsymmetrical dimeric X-ray contrast agents
Novel dimeric iodinated contrast agents with low osmolality have been prepared and evaluated with the aim of improving the already good safety profile of such agents. The aim of low osmolality was achieved, and the viscosity of these dimeric agents was also found to be beneficially lower than curren...
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Published in: | Tetrahedron letters 2011-06, Vol.52 (24), p.3068-3071 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Novel dimeric iodinated contrast agents with low osmolality have been prepared and evaluated with the aim of improving the already good safety profile of such agents. The aim of low osmolality was achieved, and the viscosity of these dimeric agents was also found to be beneficially lower than current dimeric agents in clinical use. |
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ISSN: | 0040-4039 1873-3581 |
DOI: | 10.1016/j.tetlet.2011.04.009 |