Echovirus 30 meningitis epidemic followed by an outbreak-specific RT-qPCR

Highlights • Unusual aseptic meningitis epidemic occurred in Finland. • The causative agent was identified as echovirus 30. • Echovirus 30 epidemic strain specific RT-qPCR was designed. • Echovirus 30 affected mostly adolescents.

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Bibliographic Details
Published in:Journal of clinical virology 2015-08, Vol.69, p.7-11
Main Authors: Österback, Riikka, Kalliokoski, Teemu, Lähdesmäki, Tuire, Peltola, Ville, Ruuskanen, Olli, Waris, Matti
Format: Article
Language:English
Subjects:
Adolescent
Adult
Allergy and Immunology
Cerebrospinal Fluid - virology
Child
Child, Preschool
Disease Outbreaks
Echovirus 30
Echovirus Infections - diagnosis
Echovirus Infections - epidemiology
Echovirus Infections - virology
Enterovirus
Enterovirus B, Human - classification
Enterovirus B, Human - genetics
Enterovirus B, Human - isolation & purification
Female
Finland - epidemiology
Humans
Incidence
Infant
Infant, Newborn
Infectious Disease
Male
Meningitis
Meningitis, Aseptic - epidemiology
Meningitis, Aseptic - virology
Meningitis, Viral - epidemiology
Meningitis, Viral - virology
Middle Aged
Phylogeny
Real-Time Polymerase Chain Reaction - methods
RNA, Viral - cerebrospinal fluid
RNA, Viral - genetics
RT-qPCR
Time Factors
Young Adult
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Description
Summary:Highlights • Unusual aseptic meningitis epidemic occurred in Finland. • The causative agent was identified as echovirus 30. • Echovirus 30 epidemic strain specific RT-qPCR was designed. • Echovirus 30 affected mostly adolescents.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2015.05.012