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The clinical significance of HCV core antigen detection during Telaprevir/Peg-Interferon/Ribavirin therapy in patients with HCV 1 genotype infection
Highlights • HCV core antigen in monitoring antiviral therapy. • Telaprevir therapy in patients infected with HCV genotype1. • Predictive factors of sustained virological response (SVR) in new DAA treatment.
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Published in: | Journal of clinical virology 2015-08, Vol.69, p.68-73 |
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container_title | Journal of clinical virology |
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creator | Garbuglia, Anna Rosa Lionetti, Raffaella Lapa, Daniele Taibi, Chiara Visco-Comandini, Ubaldo Montalbano, Marzia D'Offizi, Gianpiero Castiglione, Filippo Capobianchi, Maria Rosaria Paci, Paola |
description | Highlights • HCV core antigen in monitoring antiviral therapy. • Telaprevir therapy in patients infected with HCV genotype1. • Predictive factors of sustained virological response (SVR) in new DAA treatment. |
doi_str_mv | 10.1016/j.jcv.2015.06.002 |
format | article |
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subjects | Aged Allergy and Immunology Antigens, Viral - blood Antiviral Agents - therapeutic use Drug Therapy, Combination EVRearly virological response Female Genotype HCVcore antigen Hepacivirus - genetics Hepacivirus - immunology Hepacivirus - isolation & purification Hepatitis C virus Hepatitis C, Chronic - diagnosis Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - virology Humans Infectious Disease Interferon-alpha - therapeutic use Male Middle Aged Nuclear polyhedrosis virus Oligopeptides - therapeutic use Predictive Value of Tests Prospective Studies Ribavirin - therapeutic use RNA, Viral - blood ROC Curve RVRrapid virological response Sensitivity and Specificity SVRsustained virological response Telaprevir Viral Core Proteins - immunology |
title | The clinical significance of HCV core antigen detection during Telaprevir/Peg-Interferon/Ribavirin therapy in patients with HCV 1 genotype infection |
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