A monolithic 180 nm CMOS dosimeter for In Vivo Dosimetry medical application

• Published in: Radiation measurements 2014-12, Vol.71, p.389-391
• Main Authors: Villani, E.G., Crepaldi, M., DeMarchi, D., Gabrielli, A., Khan, A., Pikhay, E., Roizin, Y., Rosenfeld, A., Zhang, Z.
• Format: Article
• Language: English
• Subjects: Biocompatibility; Biomedical materials; CMOS; Design engineering; Devices; Dosimeters; Earth sciences; Earth, ocean, space; Exact sciences and technology; Geochronology; In vivo testing; In vivo tests; Isotope geochemistry. Geochronology; IVD; MICS; Surgical implants; VCO
• ISSN: 1350-4487; 1879-0925
• DOI: 10.1016/j.radmeas.2014.07.007

The design and development of a monolithic system-on-chip dosimeter fabricated in a standard 180 nm CMOS technology is described. The device is intended for real time In Vivo measurement of dose of radiation during radiotherapy sessions. Owing to its proposed small size, of approximately 1 mm3, such solution could be made in-body implantable and, as such, provide a much-enhanced high-resolution, real-time dose measurement for quality assurance in radiation therapy. The device transmits the related information on dose of radiation wirelessly to an external receiver operating in the MICS band. The various phases of this two years project, started in 2011, including the design and development of radiation sensors and integrated RF to perform the readout, will be described. •A novel monolithic CMOS dosimeter of size of 1 mm3 has been proposed.•Three different fabrications using a CMOS 180 nm technology have been carried out.•Radiation tests results showed a sensitivity of 1 cGy with accuracy better than 3%.•Preliminary RF tests showed that an RF signal is detectable in free air.