Immunoactive prebiotics transiently prevent occurrence of early atopic dermatitis among low-atopy-risk infants

[...]supplementation of OS has been limited to the first year of life in these trials.4,5,8,9,E5 Whether supraphysiologic duration of OS supplementation would have an allergy-preventive effect persisting beyond the first year is an interesting research question that has not been adequately studied y...

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Published in:Journal of allergy and clinical immunology 2015-12, Vol.136 (6), p.1696-1698.e1
Main Authors: Grüber, Christoph, MD, PhD, van Stuivenberg, Margriet, MD, MPH, Mosca, Fabio, MD, PhD, Moro, Guido, MD, PhD, Chirico, Gaetano, MD, PhD, Braegger, Christian P., MD, Riedler, Josef, MD, PhD, Yavuz, Yalcin, MSc, Boehm, Günther, MD, PhD, Wahn, Ulrich, MD, PhD
Format: Article
Language:English
Subjects:
Age
Allergy and Immunology
Babies
Birthdays
Breast Feeding
Child, Preschool
Dermatitis
Dermatitis, Atopic - prevention & control
Double-Blind Method
Families & family life
Family medical history
Female
Food
Food allergies
Humans
Infant
Infant Formula
Infections
Male
Milk
Nutrition research
Population
Prebiotics
Prevention
Risk
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Summary:[...]supplementation of OS has been limited to the first year of life in these trials.4,5,8,9,E5 Whether supraphysiologic duration of OS supplementation would have an allergy-preventive effect persisting beyond the first year is an interesting research question that has not been adequately studied yet. [...]there are indications that supplementation of infant diet in the first year of life with the immunoactive prebiotics tested here may have preventive potential against early AD, but the effect is not sustained in low-atopy-risk strata.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.07.049