Association of Central Versus Brachial Blood Pressure With Target-Organ Damage: Systematic Review and Meta-Analysis

Accumulating evidence suggests that central blood pressure (BP) may reflect the hemodynamic stress on target organs more accurately than brachial BP. A systematic review assessing the relationship of central versus brachial BP with preclinical target-organ damage was performed. Meta-analysis of cros...

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Bibliographic Details
Published in:Hypertension (Dallas, Tex. 1979) Tex. 1979), 2016-01, Vol.67 (1), p.183-190
Main Authors: Kollias, Anastasios, Lagou, Styliani, Zeniodi, Maria Elena, Boubouchairopoulou, Nadia, Stergiou, George S
Format: Article
Language:English
Subjects:
Blood Pressure - physiology
Brachial Artery - diagnostic imaging
Brachial Artery - physiopathology
Carotid Intima-Media Thickness
Humans
Hypertension - diagnosis
Hypertension - physiopathology
Hypertrophy, Left Ventricular - diagnosis
Hypertrophy, Left Ventricular - physiopathology
Pulse Wave Analysis
Risk Factors
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Summary:Accumulating evidence suggests that central blood pressure (BP) may reflect the hemodynamic stress on target organs more accurately than brachial BP. A systematic review assessing the relationship of central versus brachial BP with preclinical target-organ damage was performed. Meta-analysis of cross-sectional data showed that central compared with brachial systolic BP was more closely associated with (1) left ventricular mass index (12 studies, n=6431; weighted age [SD], 49.9 [13.1] years; 51% hypertensives): pooled correlation coefficients r=0.30; 95% confidence interval (CI), 0.23-0.37 versus r=0.26; 95% CI, 0.19-0.33, respectively; P
ISSN:0194-911X
1524-4563
DOI:10.1161/HYPERTENSIONAHA.115.06066