Role of HbA1c in predicting risk for congenital malformations

Highlights • HbA1c was assessed at first antenatal visit. • Presence of congenital malformation (CM) was noted at delivery among live births. • HbA1c at first antenatal visit was associated with CM. • Higher levels of HbA1c indicated risk for GDM. • HbA1c regardless of GDM identified risk for CM....

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Bibliographic Details
Published in:Primary care diabetes 2015-12, Vol.9 (6), p.458-464
Main Authors: Hammouda, Sahar Ali Ibrahim, Hakeem, Rubina
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biomarkers - blood
Congenital Abnormalities - blood
Congenital Abnormalities - diagnosis
Congenital Abnormalities - epidemiology
Congenital malformations
Diabetes, Gestational - blood
Diabetes, Gestational - diagnosis
Diabetes, Gestational - epidemiology
Endocrinology & Metabolism
Female
Gestational hyperglycemia
Glycated Hemoglobin A - analysis
HbA1c
Humans
Internal Medicine
Middle Aged
Prediabetic State - blood
Prediabetic State - diagnosis
Prediabetic State - epidemiology
Pregnancy
Pregnancy Outcome
Pregnancy Trimester, First - blood
Risk Assessment
Risk Factors
Saudi Arabia
Saudi Arabia - epidemiology
Up-Regulation
Young Adult
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Summary:Highlights • HbA1c was assessed at first antenatal visit. • Presence of congenital malformation (CM) was noted at delivery among live births. • HbA1c at first antenatal visit was associated with CM. • Higher levels of HbA1c indicated risk for GDM. • HbA1c regardless of GDM identified risk for CM.
ISSN:1751-9918
1878-0210
DOI:10.1016/j.pcd.2015.01.004