Skeletal Muscle Response to Endurance Training in IL-6−/− Mice

Abstract We examined effects of moderate-intensity endurance training on muscle COX/CS activities and V’O 2max in control WT and IL-6 −/− mice. Animals were exercised for 10 weeks on treadmill for 1 h, 5 days a week at velocity of 6 m·min −1 which was increased by 0.5 m·min −1 every 2 weeks up to 8 ...

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Bibliographic Details
Published in:International journal of sports medicine 2015-12, Vol.36 (14), p.1163-1169
Main Authors: Wojewoda, M., Kmiecik, K., Majerczak, J., Ventura-Clapier, R., Fortin, D., Onopiuk, M., Rog, J., Kaminski, K., Chlopicki, S., Zoladz, J. A.
Format: Article
Language:English
Subjects:
Animals
Citrate (si)-Synthase - metabolism
Cytochromes c - metabolism
Interleukin-6 - physiology
Male
Mice, Inbred C57BL
Mice, Knockout
Muscle, Skeletal - enzymology
Oxygen Consumption - physiology
Physical Conditioning, Animal
Physical Endurance - physiology
Training & Testing
Citations: Items that cite this one
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Summary:Abstract We examined effects of moderate-intensity endurance training on muscle COX/CS activities and V’O 2max in control WT and IL-6 −/− mice. Animals were exercised for 10 weeks on treadmill for 1 h, 5 days a week at velocity of 6 m·min −1 which was increased by 0.5 m·min −1 every 2 weeks up to 8 m·min −1  . Training triggered an increase of enzyme activities in soleus muscle of WT mice (COX: 480.3±8.9 U·g −1 in sedentary group vs. 773.3±62.6 U·g −1 in trained group, P
ISSN:0172-4622
1439-3964
DOI:10.1055/s-0035-1555851