Occurrence of deoxynivalenol in wheat, Hebei Province, China

• Published in: Food chemistry 2016-04, Vol.197, p.1271-1274
• Main Authors: Liu, Yinping, Lu, Yang, Wang, Liying, Chang, Fengqi, Yang, Lixin
• Format: Article
• Language: English
• Subjects: China; Chromatography, Liquid - methods; Deoxynivalenol; Flour - analysis; Humans; LC/MS/MS; Risk Assessment; Tandem Mass Spectrometry - methods; Trichothecenes - analysis; Triticum - chemistry; Wheat flour
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2015.11.047

•Eleven counties in Hebei Province were sampled over three consecutive years.•[13C15]–DON was used as the internal standard to confirm accurate quantitation.•91.5% of samples (n=672) were positive for DON, with a median value of 154μg/kg.•The ADON were far less frequently found and at lower levels.•The PDI of DON was 0.49 in 2011, 0.86 in 2012 and 0.56μg/kgbw/day in 2013. Analysis of deoxynivalenol (DON) and its metabolites 3-acetyl and 15-acetyldeoxynivalenol (3-ADON and 15-ADON) in wheat flour samples by liquid chromatography–tandem mass spectrometry (LC/MS/MS) during 2011–2013 was conducted. [13C15]–DON was used as the internal standard to accomplish as accurate as possible quantitation. Of all wheat samples (n=672), 91.5% were positive for DON, at levels ranging from 2.4 to 1130μg/kg, with a median value of 154μg/kg. The DON derivatives (3-Ac-DON, 15-Ac-DON) were far less frequently found and at lower levels than DON. The probable daily intakes (PDI) of DON (0.49 in 2011; 0.86 in 2012; 0.56 in 2013, expressed as μg/kg body weight/day) were all within the PDI of 1.0μg/kg of bw/day for DON set by Scientific Committee for Food (SCF) in 2002. Still, persistent monitoring of DON is important.