Ovarian tissue cryopreservation in children with cancer

In Wallace and colleagues' study, the selection criteria and the definition of premature ovarian insufficiency were applied identically to prepubertal and post-pubertal patients. Because of the different sensitivity of gonads to toxic treatment at different ages,7 and the report of spontaneous...

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Bibliographic Details
Published in:The lancet oncology 2014-09, Vol.15 (10), p.1049-1050
Main Author: Sarnacki, Sabine
Format: Article
Language:English
Subjects:
Cancer
Children & youth
Cryopreservation - methods
Female
Fertility
Fertility Preservation - methods
Hematology, Oncology and Palliative Medicine
Humans
Neoplasms - therapy
Ovarian Follicle
Pregnancy
Pregnancy Rate - trends
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Summary:In Wallace and colleagues' study, the selection criteria and the definition of premature ovarian insufficiency were applied identically to prepubertal and post-pubertal patients. Because of the different sensitivity of gonads to toxic treatment at different ages,7 and the report of spontaneous recovery of hormonal function after premature menopause as a result of treatment,8 the definition of high-risk for premature ovarian insufficiency and of premature ovarian insufficiency itself, as well as the modalities of follow-up, should be key points of discussion in a process of harmonisation.
ISSN:1470-2045
1474-5488
DOI:10.1016/S1470-2045(14)70378-X