Radiotherapy for elderly patients with low-risk breast cancer

In view of the known effect of this treatment on survival,5 it seems inconceivable that, in this patient population, the survival benefit would have been greater than the non-significant benefit seen for patients who received radiotherapy compared with those who did not (four vs eight breast cancer...

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Bibliographic Details
Published in:The lancet oncology 2015-05, Vol.16 (5), p.e196-e197
Main Authors: Kaidar-Person, Orit, Poortmans, Philip, Kuten, Abraham, Morgan, David A L
Format: Article
Language:English
Subjects:
Breast cancer
Breast Neoplasms - radiotherapy
Breast Neoplasms - surgery
Endocrine therapy
Female
Hematology, Oncology and Palliative Medicine
Humans
Mastectomy, Segmental
Radiation therapy
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Summary:In view of the known effect of this treatment on survival,5 it seems inconceivable that, in this patient population, the survival benefit would have been greater than the non-significant benefit seen for patients who received radiotherapy compared with those who did not (four vs eight breast cancer deaths)--ie, 1300 patients received up to 5 years (IQR 3·84-6·05) of endocrine therapy, which entails substantial morbidity,6,7 for no significant gain in survival.
ISSN:1470-2045
1474-5488
DOI:10.1016/S1470-2045(15)70063-X