AT1 receptor blockade in the central nucleus of the amygdala attenuates the effects of muscimol on sodium and water intake

Highlights • Intra-CeA losartan increased sodium intake inhibited by muscimol in WD–PR rats. • Intra-CeA losartan increased sodium intake inhibited by muscimol in FURO rats. • AT1 receptors are involved in the GABAergic regulation of salt intake in the CeA.

Saved in:
Bibliographic Details
Published in:Neuroscience 2015-10, Vol.307, p.302-310
Main Authors: Hu, B, Qiao, H, Sun, B, Jia, R, Fan, Y, Wang, N, Lu, B, Yan, J.Q
Format: Article
Language:English
Subjects:
Analysis of Variance
Angiotensin II Type 1 Receptor Blockers - pharmacology
angiotensin type-1 receptor
Animals
Central Amygdaloid Nucleus - drug effects
Central Amygdaloid Nucleus - metabolism
central nucleus of the amygdala
Choice Behavior - drug effects
Drinking - drug effects
Furosemide - pharmacology
GABA-A Receptor Agonists - pharmacology
GABAA receptor
Losartan - pharmacology
Male
Muscimol - pharmacology
Neurology
Rats
Rats, Sprague-Dawley
Receptor, Angiotensin, Type 1 - metabolism
Sodium - metabolism
sodium appetite
Sodium Potassium Chloride Symporter Inhibitors - pharmacology
Time Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Intra-CeA losartan increased sodium intake inhibited by muscimol in WD–PR rats. • Intra-CeA losartan increased sodium intake inhibited by muscimol in FURO rats. • AT1 receptors are involved in the GABAergic regulation of salt intake in the CeA.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2015.08.069