Housing condition-related changes involved in reversal learning and its c-Fos associated activity in the prefrontal cortex

Highlights • A short EE protocol improved the performance in a reversal task. • A forced exercise training, combined with the EE, did not produce a greater benefit. • Enriched groups had a specific pattern of c-Fos expression in the prefrontal cortex.

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Bibliographic Details
Published in:Neuroscience 2015-10, Vol.307, p.14-25
Main Authors: Sampedro-Piquero, P, Zancada-Menendez, C, Begega, A
Format: Article
Language:English
Subjects:
aerobic exercise
Analysis of Variance
Animals
c-Fos
cognitive flexibility
environmental enrichment
Housing
Locomotion - physiology
Male
Maze Learning - physiology
Neurology
prefrontal cortex
Prefrontal Cortex - physiology
Proto-Oncogene Proteins c-fos - metabolism
Rats
Rats, Wistar
Reaction Time - physiology
Reversal Learning - physiology
Spatial Learning - physiology
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Description
Summary:Highlights • A short EE protocol improved the performance in a reversal task. • A forced exercise training, combined with the EE, did not produce a greater benefit. • Enriched groups had a specific pattern of c-Fos expression in the prefrontal cortex.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2015.08.038