Defining Spino-Pelvic Alignment Thresholds: Should Operative Goals in Adult Spinal Deformity Surgery Account for Age?

STUDY DESIGN.Retrospective review of prospective, multicenter database. OBJECTIVE.The aim of the study was to determine age-specific spino-pelvic parameters, to extrapolate age-specific Oswestry Disability Index (ODI) values from published Short Form (SF)-36 Physical Component Score (PCS) data, and...

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Published in:Spine (Philadelphia, Pa. 1976) Pa. 1976), 2016-01, Vol.41 (1), p.62-68
Main Authors: Lafage, Renaud, Schwab, Frank, Challier, Vincent, Henry, Jensen K, Gum, Jeffrey, Smith, Justin, Hostin, Richard, Shaffrey, Christopher, Kim, Han J, Ames, Christopher, Scheer, Justin, Klineberg, Eric, Bess, Shay, Burton, Douglas, Lafage, Virginie
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Female
Humans
Male
Middle Aged
Pelvis - physiopathology
Pelvis - surgery
Quality of Life
Retrospective Studies
Severity of Illness Index
Spinal Curvatures - epidemiology
Spinal Curvatures - physiopathology
Spinal Curvatures - surgery
Spine - physiopathology
Spine - surgery
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Summary:STUDY DESIGN.Retrospective review of prospective, multicenter database. OBJECTIVE.The aim of the study was to determine age-specific spino-pelvic parameters, to extrapolate age-specific Oswestry Disability Index (ODI) values from published Short Form (SF)-36 Physical Component Score (PCS) data, and to propose age-specific realignment thresholds for adult spinal deformity (ASD). SUMMARY OF BACKGROUND DATA.The Scoliosis Research Society-Schwab classification offers a framework for defining alignment in patients with ASD. Although age-specific changes in spinal alignment and patient-reported outcomes have been established in the literature, their relationship in the setting of ASD operative realignment has not been reported. METHODS.ASD patients who received operative or nonoperative treatment were consecutively enrolled. Patients were stratified by age, consistent with published US-normative values (Norms) of the SF-36 PCS (75  y old). At baseline, relationships between between radiographic spino-pelvic parameters (lumbar-pelvic mismatch [PI-LL], pelvic tilt [PT], sagittal vertical axis [SVA], and T1 pelvic angle [TPA]), age, and PCS were established using linear regression analysis; normative PCS values were then used to establish age-specific targets. Correlation analysis with ODI and PCS was used to determine age-specific ideal alignment. RESULTS.Baseline analysis included 773 patients (53.7 y old, 54% operative, 83% female). There was a strong correlation between ODI and PCS (r = 0.814, P  0.510, P 
ISSN:0362-2436
1528-1159
DOI:10.1097/BRS.0000000000001171