Advances in imaging for diagnosis and management of cardiac sarcoidosis

Sarcoidosis is a multisystem granulomatous disorder with a high prevalence of cardiac involvement. Cardiac sarcoidosis (CS) may be life threatening due to end-stage cardiomyopathy and sudden cardiac death. The frequent absence of specific symptoms and lack of a diagnostic 'gold standard' p...

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Bibliographic Details
Published in:European heart journal cardiovascular imaging 2015-09, Vol.16 (9), p.949-958
Main Authors: Aggarwal, Niti R, Snipelisky, David, Young, Phillip M, Gersh, Bernard J, Cooper, Leslie T, Chareonthaitawee, Panithaya
Format: Article
Language:English
Subjects:
Cardiac Imaging Techniques - trends
Cardiomyopathies - diagnosis
Cardiomyopathies - mortality
Cardiomyopathies - therapy
Cause of Death
Disease-Free Survival
Early Diagnosis
Electrocardiography - methods
Electrocardiography, Ambulatory - methods
Female
Fluorodeoxyglucose F18
Forecasting
Humans
Image Interpretation, Computer-Assisted
Immunosuppressive Agents - administration & dosage
Magnetic Resonance Imaging, Cine - methods
Male
Mass Screening - methods
Positron-Emission Tomography - methods
Prognosis
Radiographic Image Enhancement - methods
Risk Assessment
Sarcoidosis - diagnosis
Sarcoidosis - mortality
Sarcoidosis - therapy
Severity of Illness Index
Survival Analysis
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Summary:Sarcoidosis is a multisystem granulomatous disorder with a high prevalence of cardiac involvement. Cardiac sarcoidosis (CS) may be life threatening due to end-stage cardiomyopathy and sudden cardiac death. The frequent absence of specific symptoms and lack of a diagnostic 'gold standard' pose challenges in the diagnosis of CS. Endomyocardial biopsy, although specific, has an unacceptably low sensitivity. Non-invasive cardiac imaging has a huge role in the assessment of patients with known or suspected CS. This comprehensive review compares the diagnostic accuracy, along with advantages and disadvantages, of established and emerging imaging modalities for CS.
ISSN:2047-2404
2047-2412
DOI:10.1093/ehjci/jev142