Hydrolytically Stable Thiol–ene Networks for Flexible Bioelectronics

Hydrolytically stable, tunable modulus polymer networks are demonstrated to survive harsh alkaline environments and offer promise for use in long-term implantable bioelectronic medicines known as electroceuticals. Today’s polymer networks (such as polyimides or polysiloxanes) succeed in providing ei...

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Bibliographic Details
Published in:ACS applied materials & interfaces 2015-12, Vol.7 (51), p.28673-28681
Main Authors: Reit, Radu, Zamorano, Daniel, Parker, Shelbi, Simon, Dustin, Lund, Benjamin, Voit, Walter, Ware, Taylor H
Format: Article
Language:English
Subjects:
Biocompatible Materials - chemistry
Elastic Modulus
Electronics - instrumentation
Hydrolysis
Kinetics
Microelectrodes
Polymers - chemistry
Siloxanes - chemistry
Sulfhydryl Compounds - chemistry
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Summary:Hydrolytically stable, tunable modulus polymer networks are demonstrated to survive harsh alkaline environments and offer promise for use in long-term implantable bioelectronic medicines known as electroceuticals. Today’s polymer networks (such as polyimides or polysiloxanes) succeed in providing either stiff or soft substrates for bioelectronics devices; however, the capability to significantly tune the modulus of such materials is lacking. Within the space of materials with easily modified elastic moduli, thiol–ene copolymers are a subset of materials that offer a promising solution to build next generation flexible bioelectronics but have typically been susceptible to hydrolytic degradation chronically. In this inquiry, we demonstrate a materials space capable of tuning the substrate modulus and explore the mechanical behavior of such networks. Furthermore, we fabricate an array of microelectrodes that can withstand accelerated aging environments shown to destroy conventional flexible bioelectronics.
ISSN:1944-8244
1944-8252
DOI:10.1021/acsami.5b10593