Effectiveness of live attenuated influenza vaccine and inactivated influenza vaccine in children 2–17 years of age in 2013–2014 in the United States

Highlights • This study assesses quadrivalent LAIV effectiveness in children. • LAIV provided significant protection against B/Yamagata, but not A/H1N1pdm09. • A new and more heat-stable A/H1N1pdm09 LAIV strain is proposed for 2015–2016.

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Bibliographic Details
Published in:Vaccine 2016-01, Vol.34 (1), p.77-82
Main Authors: Caspard, Herve, Gaglani, Manjusha, Clipper, Lydia, Belongia, Edward A, McLean, Huong Q, Griffin, Marie R, Talbot, H. Keipp, Poehling, Katherine A, Peters, Timothy R, Veney, Naomi, Ambrose, Christopher S
Format: Article
Language:English
Subjects:
Adolescent
Adolescents
Age groups
Allergy and Immunology
Child
Child, Preschool
Children
Estimates
Female
Health insurance
Humans
Illnesses
Immunization
Influenza
Influenza Vaccines - administration & dosage
Influenza Vaccines - immunology
Influenza, Human - epidemiology
Influenza, Human - prevention & control
Laboratories
LAIV
Male
Observational studies
Pediatrics
Quadrivalent live attenuated influenza vaccine
Treatment Outcome
United States - epidemiology
Vaccines
Vaccines, Attenuated - administration & dosage
Vaccines, Attenuated - immunology
Vaccines, Inactivated - administration & dosage
Vaccines, Inactivated - immunology
Variables
Viruses
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Description
Summary:Highlights • This study assesses quadrivalent LAIV effectiveness in children. • LAIV provided significant protection against B/Yamagata, but not A/H1N1pdm09. • A new and more heat-stable A/H1N1pdm09 LAIV strain is proposed for 2015–2016.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2015.11.010