Expanding the MDx toolbox for filarial diagnosis and surveillance

Highlights • Accurate parasite detection is essential for filariasis control. • Current tools are inadequate to detect low parasite numbers in humans and vectors. • We discuss prospects for developing new tools based on nucleic acid detection. • We focus on isothermal nucleic acid amplification meth...

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Bibliographic Details
Published in:Trends in parasitology 2015-08, Vol.31 (8), p.391-400
Main Authors: Alhassan, Andy, Li, Zhiru, Poole, Catherine B, Carlow, Clotilde K.S
Format: Article
Language:English
Subjects:
Animals
Arthropoda
filariasis
Filariasis - diagnosis
Filariasis - parasitology
Filariasis - prevention & control
Gastroenterology and Hepatology
Humans
Immunologic Tests
Infectious Disease
isothermal amplification
Molecular Diagnostic Techniques - standards
Molecular Diagnostic Techniques - trends
molecular diagnostics
Nematoda
Nucleic Acid Amplification Techniques
Population Surveillance
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Summary:Highlights • Accurate parasite detection is essential for filariasis control. • Current tools are inadequate to detect low parasite numbers in humans and vectors. • We discuss prospects for developing new tools based on nucleic acid detection. • We focus on isothermal nucleic acid amplification methods suitable for field use.
ISSN:1471-4922
1471-5007
DOI:10.1016/j.pt.2015.04.006