Effects of some endocrine disruptors on cell cycle progression and murine dendritic cell differentiation

Highlights ► EDCs mimic hormone function inducing diseases in exposed organisms. ► The effects of some EDCs of phenolic origin has been assessed in vitro. ► The effects on cell proliferation and differentiation were studied. ► The oestrogenic ranking between the used endocrine disruptors have been e...

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Bibliographic Details
Published in:General and comparative endocrinology 2012-08, Vol.178 (1), p.54-63
Main Authors: Pisapia, L, Del Pozzo, G, Barba, P, Caputo, L, Mita, L, Viggiano, E, Russo, G.L, Nicolucci, C, Rossi, S, Bencivenga, U, Mita, D.G, Diano, N
Format: Article
Language:English
Subjects:
Animals
Benzhydryl Compounds
Cell cycle
Cell Cycle - drug effects
Cell differentiation
Cell Differentiation - drug effects
Cell Line, Tumor
Cells, Cultured
Dendritic cells
Dendritic Cells - cytology
Dendritic Cells - drug effects
Endocrine disruptors
Endocrine Disruptors - pharmacology
Endocrinology & Metabolism
Female
Humans
MCF-7
Mice
Mice, Inbred C57BL
Phenols - pharmacology
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Summary:Highlights ► EDCs mimic hormone function inducing diseases in exposed organisms. ► The effects of some EDCs of phenolic origin has been assessed in vitro. ► The effects on cell proliferation and differentiation were studied. ► The oestrogenic ranking between the used endocrine disruptors have been established.
ISSN:0016-6480
1095-6840
DOI:10.1016/j.ygcen.2012.04.005