Cell and in Vivo Imaging of Fluoride Ion with Highly Selective Bioluminescent Probes

Two rapid bioluminescent probes for the detection of fluoride ion were developed on the basis of F–Si bond formation herein. It should be noted that probe 1 exhibited highly selective and sensitive detection toward fluoride ion over other anions and has been successfully applied in imaging fluoride...

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Bibliographic Details
Published in:Analytical chemistry (Washington) 2015-09, Vol.87 (18), p.9110-9113
Main Authors: Ke, Bowen, Wu, Wenxiao, Wei, Liu, Wu, Fengbo, Chen, Guo, He, Gu, Li, Minyong
Format: Article
Language:English
Subjects:
Analytical chemistry
Animals
Biocompatibility
Biomedical materials
Bonding
Cell Line
Cell Survival
Cells
Chemical bonds
Fluorides
Fluorides - analysis
Fluorides - chemistry
Imaging
In vivo testing
In vivo tests
Ions
Luminescent Agents - chemistry
Mice
Molecular Imaging - methods
Silicon - chemistry
Surgical implants
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Description
Summary:Two rapid bioluminescent probes for the detection of fluoride ion were developed on the basis of F–Si bond formation herein. It should be noted that probe 1 exhibited highly selective and sensitive detection toward fluoride ion over other anions and has been successfully applied in imaging fluoride ion in both living cells and animals.
ISSN:0003-2700
1520-6882
DOI:10.1021/acs.analchem.5b02237