Effect of lipopolysaccharide (LPS) from Ochrobactrum intermedium on sheep experimentally infected with Fasciola hepatica

The effects of the lipopolysaccharide (LPS) from Ochrobactrum intermedium was evaluated in sheep experimentally infected with Fasciola hepatica . Animals were divided into four groups: two treated with the LPS (T1/T2) and two controls (C1/C2). T1/C1 were slaughtered at 30 days postinfection (dpi) an...

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Bibliographic Details
Published in:Parasitology research (1987) 2013-08, Vol.112 (8), p.2913-2923
Main Authors: Martínez-Pérez, J. M., Robles-Pérez, D., Valcárcel-Sancho, F., González-Guirado, A. M., de Castro, I. Casanova-García, Nieto-Martínez, J. M., Rojo-Vázquez, F. A., Martínez-Valladares, M.
Format: Article
Language:English
Subjects:
Animals
Biomedical and Life Sciences
Biomedicine
Fasciola hepatica
Fasciola hepatica - immunology
Fascioliasis - drug therapy
Fascioliasis - parasitology
Fascioliasis - veterinary
Health aspects
Host-parasite relationships
Immunologic Factors - pharmacology
Immunology
Immunomodulation - immunology
Lipopolysaccharides
Lipopolysaccharides - pharmacology
Medical Microbiology
Microbiology
Ochrobactrum
Original Paper
Physiological aspects
Sheep
Sheep Diseases - drug therapy
Sheep Diseases - parasitology
Trematoda
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Summary:The effects of the lipopolysaccharide (LPS) from Ochrobactrum intermedium was evaluated in sheep experimentally infected with Fasciola hepatica . Animals were divided into four groups: two treated with the LPS (T1/T2) and two controls (C1/C2). T1/C1 were slaughtered at 30 days postinfection (dpi) and T2/C2 at 85 dpi. Body weight and body condition were found higher in T1 and T2 than in controls, although differences were not significant. Treated sheep showed lower cumulative fecal egg count than controls ( p  
ISSN:0932-0113
1432-1955
DOI:10.1007/s00436-013-3463-7