Online determination of biophysical parameters of mucous membranes of a human body

We have developed a method for online determination of biophysical parameters of mucous membranes (MMs) of a human body (transport scattering coefficient, scattering anisotropy factor, haemoglobin concentration, degrees of blood oxygenation, average diameter of capillaries with blood) from measureme...

Full description

Saved in:
Bibliographic Details
Published in:Quantum electronics (Woodbury, N.Y.) N.Y.), 2013-01, Vol.43 (7), p.683-689
Main Authors: Lisenko, S.A., Kugeiko, M.M.
Format: Article
Language:English
Subjects:
ANIMAL TISSUES
ANISOTROPY
biophysical parameters
BLOOD
CALIBRATION
CAPILLARIES
CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS
CONCENTRATION RATIO
diffuse reflectance
Diffusion
endoscopy
FIBER OPTICS
Haemoglobin
HEMOGLOBIN
Human body
inverse problem
LASERS
MEDICINE
mucous membrane
MUCOUS MEMBRANES
multiple regressions
Online
Optical fibers
optical measurements
optical parameters
RADIATION TRANSPORT
RADIOLOGY AND NUCLEAR MEDICINE
SCATTERING
SIGNALS
SIMULATION
Spectra
VISIBLE RADIATION
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We have developed a method for online determination of biophysical parameters of mucous membranes (MMs) of a human body (transport scattering coefficient, scattering anisotropy factor, haemoglobin concentration, degrees of blood oxygenation, average diameter of capillaries with blood) from measurements of spectral and spatial characteristics of diffuse reflection. The method is based on regression relationships between linearly independent components of the measured light signals and the unknown parameters of MMs, obtained by simulation of the radiation transfer in the MM under conditions of its general variability. We have proposed and justified the calibration-free fibre-optic method for determining the concentration of haemoglobin in MMs by measuring the light signals diffusely reflected by the tissue in four spectral regions at two different distances from the illumination spot. We have selected the optimal wavelengths of optical probing for the implementation of the method.
ISSN:1063-7818
1468-4799
DOI:10.1070/QE2013v043n07ABEH014951