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Online determination of biophysical parameters of mucous membranes of a human body
We have developed a method for online determination of biophysical parameters of mucous membranes (MMs) of a human body (transport scattering coefficient, scattering anisotropy factor, haemoglobin concentration, degrees of blood oxygenation, average diameter of capillaries with blood) from measureme...
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| Published in: | Quantum electronics (Woodbury, N.Y.) N.Y.), 2013-01, Vol.43 (7), p.683-689 |
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| cites | cdi_FETCH-LOGICAL-c337t-588e533096280f769541bbebd51f8024b68462a2ad8ec57df9e554a4a6cea8253 |
| container_end_page | 689 |
| container_issue | 7 |
| container_start_page | 683 |
| container_title | Quantum electronics (Woodbury, N.Y.) |
| container_volume | 43 |
| creator | Lisenko, S.A. Kugeiko, M.M. |
| description | We have developed a method for online determination of biophysical parameters of mucous membranes (MMs) of a human body (transport scattering coefficient, scattering anisotropy factor, haemoglobin concentration, degrees of blood oxygenation, average diameter of capillaries with blood) from measurements of spectral and spatial characteristics of diffuse reflection. The method is based on regression relationships between linearly independent components of the measured light signals and the unknown parameters of MMs, obtained by simulation of the radiation transfer in the MM under conditions of its general variability. We have proposed and justified the calibration-free fibre-optic method for determining the concentration of haemoglobin in MMs by measuring the light signals diffusely reflected by the tissue in four spectral regions at two different distances from the illumination spot. We have selected the optimal wavelengths of optical probing for the implementation of the method. |
| doi_str_mv | 10.1070/QE2013v043n07ABEH014951 |
| format | article |
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The method is based on regression relationships between linearly independent components of the measured light signals and the unknown parameters of MMs, obtained by simulation of the radiation transfer in the MM under conditions of its general variability. We have proposed and justified the calibration-free fibre-optic method for determining the concentration of haemoglobin in MMs by measuring the light signals diffusely reflected by the tissue in four spectral regions at two different distances from the illumination spot. We have selected the optimal wavelengths of optical probing for the implementation of the method.</description><identifier>ISSN: 1063-7818</identifier><identifier>EISSN: 1468-4799</identifier><identifier>DOI: 10.1070/QE2013v043n07ABEH014951</identifier><language>eng</language><publisher>United States: Turpion Ltd and the Russian Academy of Sciences</publisher><subject>ANIMAL TISSUES ; ANISOTROPY ; biophysical parameters ; BLOOD ; CALIBRATION ; CAPILLARIES ; CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS ; CONCENTRATION RATIO ; diffuse reflectance ; Diffusion ; endoscopy ; FIBER OPTICS ; Haemoglobin ; HEMOGLOBIN ; Human body ; inverse problem ; LASERS ; MEDICINE ; mucous membrane ; MUCOUS MEMBRANES ; multiple regressions ; Online ; Optical fibers ; optical measurements ; optical parameters ; RADIATION TRANSPORT ; RADIOLOGY AND NUCLEAR MEDICINE ; SCATTERING ; SIGNALS ; SIMULATION ; Spectra ; VISIBLE RADIATION</subject><ispartof>Quantum electronics (Woodbury, N.Y.), 2013-01, Vol.43 (7), p.683-689</ispartof><rights>2013 Kvantovaya Elektronika and Turpion Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c337t-588e533096280f769541bbebd51f8024b68462a2ad8ec57df9e554a4a6cea8253</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27903,27904</link.rule.ids><backlink>$$Uhttps://www.osti.gov/biblio/22156613$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Lisenko, S.A.</creatorcontrib><creatorcontrib>Kugeiko, M.M.</creatorcontrib><title>Online determination of biophysical parameters of mucous membranes of a human body</title><title>Quantum electronics (Woodbury, N.Y.)</title><addtitle>QEL</addtitle><addtitle>Quantum Electron</addtitle><description>We have developed a method for online determination of biophysical parameters of mucous membranes (MMs) of a human body (transport scattering coefficient, scattering anisotropy factor, haemoglobin concentration, degrees of blood oxygenation, average diameter of capillaries with blood) from measurements of spectral and spatial characteristics of diffuse reflection. The method is based on regression relationships between linearly independent components of the measured light signals and the unknown parameters of MMs, obtained by simulation of the radiation transfer in the MM under conditions of its general variability. We have proposed and justified the calibration-free fibre-optic method for determining the concentration of haemoglobin in MMs by measuring the light signals diffusely reflected by the tissue in four spectral regions at two different distances from the illumination spot. We have selected the optimal wavelengths of optical probing for the implementation of the method.</description><subject>ANIMAL TISSUES</subject><subject>ANISOTROPY</subject><subject>biophysical parameters</subject><subject>BLOOD</subject><subject>CALIBRATION</subject><subject>CAPILLARIES</subject><subject>CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS</subject><subject>CONCENTRATION RATIO</subject><subject>diffuse reflectance</subject><subject>Diffusion</subject><subject>endoscopy</subject><subject>FIBER OPTICS</subject><subject>Haemoglobin</subject><subject>HEMOGLOBIN</subject><subject>Human body</subject><subject>inverse problem</subject><subject>LASERS</subject><subject>MEDICINE</subject><subject>mucous membrane</subject><subject>MUCOUS MEMBRANES</subject><subject>multiple regressions</subject><subject>Online</subject><subject>Optical fibers</subject><subject>optical measurements</subject><subject>optical parameters</subject><subject>RADIATION TRANSPORT</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>SCATTERING</subject><subject>SIGNALS</subject><subject>SIMULATION</subject><subject>Spectra</subject><subject>VISIBLE RADIATION</subject><issn>1063-7818</issn><issn>1468-4799</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqFkE9LxDAQxYsouKz7GSzowUs1_5Me12V1hYVF0XNI05SNtElNWmG_vVnrUfE0w8zvDfNell1CcAsBB3fPawQg_gQEO8CX9-sNgKSk8CSbQcJEQXhZnqYeMFxwAcV5tojRVoASAqhgYpa97FxrnclrM5jQWacG613um7yyvt8fotWqzXsVVHcE4nHTjdqPMe9MVwXlzPdM5fuxUy6vfH24yM4a1Uaz-Knz7O1h_braFNvd49NquS00xnwoqBCGYgxKhgRoOCspgVVlqprCRgBEKiYIQwqpWhhNed2UhlKiiGLaKIEonmdX010fByujtoPRe-2dM3qQCEHKGMSJupmoPviP0cRBdjZq07bp9WRDQk4xRSUvWUL5hOrgYwymkX2wnQoHCYE8xi3_iDsprydlCk2--zG4ZDzRW0mw5JIJLPu6SRj-Bfvv-Bcc0Y6z</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Lisenko, S.A.</creator><creator>Kugeiko, M.M.</creator><general>Turpion Ltd and the Russian Academy of Sciences</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SC</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>H8D</scope><scope>JQ2</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>OTOTI</scope></search><sort><creationdate>20130101</creationdate><title>Online determination of biophysical parameters of mucous membranes of a human body</title><author>Lisenko, S.A. ; Kugeiko, M.M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c337t-588e533096280f769541bbebd51f8024b68462a2ad8ec57df9e554a4a6cea8253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>ANIMAL TISSUES</topic><topic>ANISOTROPY</topic><topic>biophysical parameters</topic><topic>BLOOD</topic><topic>CALIBRATION</topic><topic>CAPILLARIES</topic><topic>CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS</topic><topic>CONCENTRATION RATIO</topic><topic>diffuse reflectance</topic><topic>Diffusion</topic><topic>endoscopy</topic><topic>FIBER OPTICS</topic><topic>Haemoglobin</topic><topic>HEMOGLOBIN</topic><topic>Human body</topic><topic>inverse problem</topic><topic>LASERS</topic><topic>MEDICINE</topic><topic>mucous membrane</topic><topic>MUCOUS MEMBRANES</topic><topic>multiple regressions</topic><topic>Online</topic><topic>Optical fibers</topic><topic>optical measurements</topic><topic>optical parameters</topic><topic>RADIATION TRANSPORT</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>SCATTERING</topic><topic>SIGNALS</topic><topic>SIMULATION</topic><topic>Spectra</topic><topic>VISIBLE RADIATION</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lisenko, S.A.</creatorcontrib><creatorcontrib>Kugeiko, M.M.</creatorcontrib><collection>CrossRef</collection><collection>Computer and Information Systems Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts – Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>OSTI.GOV</collection><jtitle>Quantum electronics (Woodbury, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lisenko, S.A.</au><au>Kugeiko, M.M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Online determination of biophysical parameters of mucous membranes of a human body</atitle><jtitle>Quantum electronics (Woodbury, N.Y.)</jtitle><stitle>QEL</stitle><addtitle>Quantum Electron</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>43</volume><issue>7</issue><spage>683</spage><epage>689</epage><pages>683-689</pages><issn>1063-7818</issn><eissn>1468-4799</eissn><abstract>We have developed a method for online determination of biophysical parameters of mucous membranes (MMs) of a human body (transport scattering coefficient, scattering anisotropy factor, haemoglobin concentration, degrees of blood oxygenation, average diameter of capillaries with blood) from measurements of spectral and spatial characteristics of diffuse reflection. The method is based on regression relationships between linearly independent components of the measured light signals and the unknown parameters of MMs, obtained by simulation of the radiation transfer in the MM under conditions of its general variability. We have proposed and justified the calibration-free fibre-optic method for determining the concentration of haemoglobin in MMs by measuring the light signals diffusely reflected by the tissue in four spectral regions at two different distances from the illumination spot. We have selected the optimal wavelengths of optical probing for the implementation of the method.</abstract><cop>United States</cop><pub>Turpion Ltd and the Russian Academy of Sciences</pub><doi>10.1070/QE2013v043n07ABEH014951</doi><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 1063-7818 |
| ispartof | Quantum electronics (Woodbury, N.Y.), 2013-01, Vol.43 (7), p.683-689 |
| issn | 1063-7818 1468-4799 |
| language | eng |
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| source | Institute of Physics |
| subjects | ANIMAL TISSUES ANISOTROPY biophysical parameters BLOOD CALIBRATION CAPILLARIES CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS CONCENTRATION RATIO diffuse reflectance Diffusion endoscopy FIBER OPTICS Haemoglobin HEMOGLOBIN Human body inverse problem LASERS MEDICINE mucous membrane MUCOUS MEMBRANES multiple regressions Online Optical fibers optical measurements optical parameters RADIATION TRANSPORT RADIOLOGY AND NUCLEAR MEDICINE SCATTERING SIGNALS SIMULATION Spectra VISIBLE RADIATION |
| title | Online determination of biophysical parameters of mucous membranes of a human body |
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