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The Effect of Laparoscopic Sleeve Gastrectomy with Concomitant Hiatal Hernia Repair on Gastroesophageal Reflux Disease in the Morbidly Obese
Background The effect of laparoscopic sleeve gastrectomy (LSG) on gastroesophageal reflux disease (GERD) is controversial. Although concomitant hiatal hernia repair (HHR) at the time of LSG is common and advocated by many, there are few data on the outcomes of GERD symptoms in these patients. The ai...
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Published in: | Obesity surgery 2016-01, Vol.26 (1), p.61-66 |
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creator | Samakar, Kamran McKenzie, Travis J. Tavakkoli, Ali Vernon, Ashley H. Robinson, Malcolm K. Shikora, Scott A. |
description | Background
The effect of laparoscopic sleeve gastrectomy (LSG) on gastroesophageal reflux disease (GERD) is controversial. Although concomitant hiatal hernia repair (HHR) at the time of LSG is common and advocated by many, there are few data on the outcomes of GERD symptoms in these patients. The aim of this study was to evaluate the effect of concomitant HHR on GERD symptoms in morbidly obese patients undergoing LSG.
Methods
A single institution, multi-surgeon, prospectively maintained database was examined to identify patients who underwent LSG and concomitant HHR from December 2010 to October 2013. Patient characteristics, operative details, and postoperative outcomes were analyzed. Standardized patient questionnaires administered both pre- and postoperatively were utilized. Primary endpoints included subjective reflux symptoms and the need for antisecretory therapy. Weight loss was considered a secondary endpoint.
Results
Fifty-eight patients were identified meeting inclusion criteria (LSG + HHR), with a mean follow-up of 97.5 weeks (range 44–172 weeks). The mean age of the cohort was 49.5 ± 11.2 years, with 74.1 % being female. Mean preoperative BMI was 44.2 ± 6.6 kg/m
2
. Preoperative upper gastrointestinal contrast series was performed in all patients and demonstrated a hiatal hernia in 34.5 % of patients and reflux in 15.5 % of patients. Preoperatively, 34.6 % (
n
= 26) of patients reported subjective symptoms of reflux and/or required daily antisecretory therapy. After LSG + HHR, 34.6 % of symptomatic patients had resolution of their symptoms off therapy while the rest remained symptomatic and required daily antisecretory therapy; 84.4 % of patients that were asymptomatic preoperatively remained asymptomatic after surgery. New onset reflux symptoms requiring daily antisecretory therapy was seen in 15.6 % of patients who were previously asymptomatic. Post surgical weight loss did not correlate with the presence or resolution of reflux symptoms.
Conclusion
Based on our data, LSG with concomitant HHR improved GERD symptoms or the need for daily antisecretory therapy only in a third of symptomatic patients. Furthermore, 15.6 % of asymptomatic patients developed de novo GERD symptoms despite a HHR. In patients with a documented hiatal hernia, HHR does not lead to GERD resolution or prevention after LSG, indicating the need for appropriate patient counseling and further study. |
doi_str_mv | 10.1007/s11695-015-1737-0 |
format | article |
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The effect of laparoscopic sleeve gastrectomy (LSG) on gastroesophageal reflux disease (GERD) is controversial. Although concomitant hiatal hernia repair (HHR) at the time of LSG is common and advocated by many, there are few data on the outcomes of GERD symptoms in these patients. The aim of this study was to evaluate the effect of concomitant HHR on GERD symptoms in morbidly obese patients undergoing LSG.
Methods
A single institution, multi-surgeon, prospectively maintained database was examined to identify patients who underwent LSG and concomitant HHR from December 2010 to October 2013. Patient characteristics, operative details, and postoperative outcomes were analyzed. Standardized patient questionnaires administered both pre- and postoperatively were utilized. Primary endpoints included subjective reflux symptoms and the need for antisecretory therapy. Weight loss was considered a secondary endpoint.
Results
Fifty-eight patients were identified meeting inclusion criteria (LSG + HHR), with a mean follow-up of 97.5 weeks (range 44–172 weeks). The mean age of the cohort was 49.5 ± 11.2 years, with 74.1 % being female. Mean preoperative BMI was 44.2 ± 6.6 kg/m
2
. Preoperative upper gastrointestinal contrast series was performed in all patients and demonstrated a hiatal hernia in 34.5 % of patients and reflux in 15.5 % of patients. Preoperatively, 34.6 % (
n
= 26) of patients reported subjective symptoms of reflux and/or required daily antisecretory therapy. After LSG + HHR, 34.6 % of symptomatic patients had resolution of their symptoms off therapy while the rest remained symptomatic and required daily antisecretory therapy; 84.4 % of patients that were asymptomatic preoperatively remained asymptomatic after surgery. New onset reflux symptoms requiring daily antisecretory therapy was seen in 15.6 % of patients who were previously asymptomatic. Post surgical weight loss did not correlate with the presence or resolution of reflux symptoms.
Conclusion
Based on our data, LSG with concomitant HHR improved GERD symptoms or the need for daily antisecretory therapy only in a third of symptomatic patients. Furthermore, 15.6 % of asymptomatic patients developed de novo GERD symptoms despite a HHR. In patients with a documented hiatal hernia, HHR does not lead to GERD resolution or prevention after LSG, indicating the need for appropriate patient counseling and further study.</description><identifier>ISSN: 0960-8923</identifier><identifier>EISSN: 1708-0428</identifier><identifier>DOI: 10.1007/s11695-015-1737-0</identifier><identifier>PMID: 25990380</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adult ; Aged ; Antacids - administration & dosage ; Drug Administration Schedule ; Female ; Gastrectomy - adverse effects ; Gastrectomy - methods ; Gastroesophageal reflux ; Gastroesophageal Reflux - drug therapy ; Gastroesophageal Reflux - etiology ; Gastroesophageal Reflux - surgery ; Gastrointestinal surgery ; Hernia, Hiatal - complications ; Hernia, Hiatal - surgery ; Hernias ; Herniorrhaphy ; Humans ; Laparoscopy - adverse effects ; Laparoscopy - methods ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Morbidity ; Obesity ; Obesity, Morbid - complications ; Obesity, Morbid - surgery ; Original Contributions ; Retrospective Studies ; Surgery ; Treatment Outcome ; Weight Loss ; Young Adult</subject><ispartof>Obesity surgery, 2016-01, Vol.26 (1), p.61-66</ispartof><rights>Springer Science+Business Media New York 2015</rights><rights>Springer Science+Business Media New York 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-604f908908ca18da6b9468c3ebbede86c03337269efddbae0611edddfd3d1c463</citedby><cites>FETCH-LOGICAL-c405t-604f908908ca18da6b9468c3ebbede86c03337269efddbae0611edddfd3d1c463</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25990380$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Samakar, Kamran</creatorcontrib><creatorcontrib>McKenzie, Travis J.</creatorcontrib><creatorcontrib>Tavakkoli, Ali</creatorcontrib><creatorcontrib>Vernon, Ashley H.</creatorcontrib><creatorcontrib>Robinson, Malcolm K.</creatorcontrib><creatorcontrib>Shikora, Scott A.</creatorcontrib><title>The Effect of Laparoscopic Sleeve Gastrectomy with Concomitant Hiatal Hernia Repair on Gastroesophageal Reflux Disease in the Morbidly Obese</title><title>Obesity surgery</title><addtitle>OBES SURG</addtitle><addtitle>Obes Surg</addtitle><description>Background
The effect of laparoscopic sleeve gastrectomy (LSG) on gastroesophageal reflux disease (GERD) is controversial. Although concomitant hiatal hernia repair (HHR) at the time of LSG is common and advocated by many, there are few data on the outcomes of GERD symptoms in these patients. The aim of this study was to evaluate the effect of concomitant HHR on GERD symptoms in morbidly obese patients undergoing LSG.
Methods
A single institution, multi-surgeon, prospectively maintained database was examined to identify patients who underwent LSG and concomitant HHR from December 2010 to October 2013. Patient characteristics, operative details, and postoperative outcomes were analyzed. Standardized patient questionnaires administered both pre- and postoperatively were utilized. Primary endpoints included subjective reflux symptoms and the need for antisecretory therapy. Weight loss was considered a secondary endpoint.
Results
Fifty-eight patients were identified meeting inclusion criteria (LSG + HHR), with a mean follow-up of 97.5 weeks (range 44–172 weeks). The mean age of the cohort was 49.5 ± 11.2 years, with 74.1 % being female. Mean preoperative BMI was 44.2 ± 6.6 kg/m
2
. Preoperative upper gastrointestinal contrast series was performed in all patients and demonstrated a hiatal hernia in 34.5 % of patients and reflux in 15.5 % of patients. Preoperatively, 34.6 % (
n
= 26) of patients reported subjective symptoms of reflux and/or required daily antisecretory therapy. After LSG + HHR, 34.6 % of symptomatic patients had resolution of their symptoms off therapy while the rest remained symptomatic and required daily antisecretory therapy; 84.4 % of patients that were asymptomatic preoperatively remained asymptomatic after surgery. New onset reflux symptoms requiring daily antisecretory therapy was seen in 15.6 % of patients who were previously asymptomatic. Post surgical weight loss did not correlate with the presence or resolution of reflux symptoms.
Conclusion
Based on our data, LSG with concomitant HHR improved GERD symptoms or the need for daily antisecretory therapy only in a third of symptomatic patients. Furthermore, 15.6 % of asymptomatic patients developed de novo GERD symptoms despite a HHR. In patients with a documented hiatal hernia, HHR does not lead to GERD resolution or prevention after LSG, indicating the need for appropriate patient counseling and further study.</description><subject>Adult</subject><subject>Aged</subject><subject>Antacids - administration & dosage</subject><subject>Drug Administration Schedule</subject><subject>Female</subject><subject>Gastrectomy - adverse effects</subject><subject>Gastrectomy - methods</subject><subject>Gastroesophageal reflux</subject><subject>Gastroesophageal Reflux - drug therapy</subject><subject>Gastroesophageal Reflux - etiology</subject><subject>Gastroesophageal Reflux - surgery</subject><subject>Gastrointestinal surgery</subject><subject>Hernia, Hiatal - complications</subject><subject>Hernia, Hiatal - surgery</subject><subject>Hernias</subject><subject>Herniorrhaphy</subject><subject>Humans</subject><subject>Laparoscopy - adverse effects</subject><subject>Laparoscopy - methods</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Morbidity</subject><subject>Obesity</subject><subject>Obesity, Morbid - complications</subject><subject>Obesity, Morbid - surgery</subject><subject>Original Contributions</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><subject>Weight Loss</subject><subject>Young Adult</subject><issn>0960-8923</issn><issn>1708-0428</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNp1kdGK1DAUhoMo7rj6AN5IwBtvqidJm7aXMrvuCCML63pd0uRkJ0vb1CRV5x18aDN0FRGEQC7O9_8n5CPkJYO3DKB-FxmTbVUAqwpWi7qAR2TDamgKKHnzmGyglVA0LRdn5FmM9wCcSc6fkjNetS2IBjbk5-0B6aW1qBP1lu7VrIKP2s9O088D4jekVyqmkOd-PNLvLh3o1k_ajy6pKdGdU0kNdIdhcore4KxcoH5aQx6jnw_qDjNxg3ZYftALF1FFpG6iKW_-5EPvzHCk1z1GfE6eWDVEfPFwn5MvHy5vt7tif331cft-X-gSqlRIKG0LTT5ascYo2belbLTAvkeDjdQghKi5bNEa0ysEyRgaY6wRhulSinPyZu2dg_-6YEzd6KLGYVAT-iV2rK5KaGomRUZf_4Pe-yVM-XUnSnCAsjpRbKV0_rwY0HZzcKMKx45Bd1LVraq6rKo7qeogZ149NC_9iOZP4rebDPAViHk03WH4a_V_W38Bq92gRQ</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Samakar, Kamran</creator><creator>McKenzie, Travis J.</creator><creator>Tavakkoli, Ali</creator><creator>Vernon, Ashley H.</creator><creator>Robinson, Malcolm K.</creator><creator>Shikora, Scott A.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20160101</creationdate><title>The Effect of Laparoscopic Sleeve Gastrectomy with Concomitant Hiatal Hernia Repair on Gastroesophageal Reflux Disease in the Morbidly Obese</title><author>Samakar, Kamran ; 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The effect of laparoscopic sleeve gastrectomy (LSG) on gastroesophageal reflux disease (GERD) is controversial. Although concomitant hiatal hernia repair (HHR) at the time of LSG is common and advocated by many, there are few data on the outcomes of GERD symptoms in these patients. The aim of this study was to evaluate the effect of concomitant HHR on GERD symptoms in morbidly obese patients undergoing LSG.
Methods
A single institution, multi-surgeon, prospectively maintained database was examined to identify patients who underwent LSG and concomitant HHR from December 2010 to October 2013. Patient characteristics, operative details, and postoperative outcomes were analyzed. Standardized patient questionnaires administered both pre- and postoperatively were utilized. Primary endpoints included subjective reflux symptoms and the need for antisecretory therapy. Weight loss was considered a secondary endpoint.
Results
Fifty-eight patients were identified meeting inclusion criteria (LSG + HHR), with a mean follow-up of 97.5 weeks (range 44–172 weeks). The mean age of the cohort was 49.5 ± 11.2 years, with 74.1 % being female. Mean preoperative BMI was 44.2 ± 6.6 kg/m
2
. Preoperative upper gastrointestinal contrast series was performed in all patients and demonstrated a hiatal hernia in 34.5 % of patients and reflux in 15.5 % of patients. Preoperatively, 34.6 % (
n
= 26) of patients reported subjective symptoms of reflux and/or required daily antisecretory therapy. After LSG + HHR, 34.6 % of symptomatic patients had resolution of their symptoms off therapy while the rest remained symptomatic and required daily antisecretory therapy; 84.4 % of patients that were asymptomatic preoperatively remained asymptomatic after surgery. New onset reflux symptoms requiring daily antisecretory therapy was seen in 15.6 % of patients who were previously asymptomatic. Post surgical weight loss did not correlate with the presence or resolution of reflux symptoms.
Conclusion
Based on our data, LSG with concomitant HHR improved GERD symptoms or the need for daily antisecretory therapy only in a third of symptomatic patients. Furthermore, 15.6 % of asymptomatic patients developed de novo GERD symptoms despite a HHR. In patients with a documented hiatal hernia, HHR does not lead to GERD resolution or prevention after LSG, indicating the need for appropriate patient counseling and further study.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>25990380</pmid><doi>10.1007/s11695-015-1737-0</doi><tpages>6</tpages></addata></record> |
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subjects | Adult Aged Antacids - administration & dosage Drug Administration Schedule Female Gastrectomy - adverse effects Gastrectomy - methods Gastroesophageal reflux Gastroesophageal Reflux - drug therapy Gastroesophageal Reflux - etiology Gastroesophageal Reflux - surgery Gastrointestinal surgery Hernia, Hiatal - complications Hernia, Hiatal - surgery Hernias Herniorrhaphy Humans Laparoscopy - adverse effects Laparoscopy - methods Male Medicine Medicine & Public Health Middle Aged Morbidity Obesity Obesity, Morbid - complications Obesity, Morbid - surgery Original Contributions Retrospective Studies Surgery Treatment Outcome Weight Loss Young Adult |
title | The Effect of Laparoscopic Sleeve Gastrectomy with Concomitant Hiatal Hernia Repair on Gastroesophageal Reflux Disease in the Morbidly Obese |
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