Targeted phototherapy

Background: Targeted phototherapy is a new form of phototherapy which has many advantages and disadvantages over conventional phototherapy. This article reviews the different technologies and outlines recommendations based on current evidence. Methods: A literature search was performed on targeted p...

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Bibliographic Details
Published in:Indian journal of dermatology, venereology, and leprology venereology, and leprology, 2016-01, Vol.82 (1), p.1-6
Main Authors: Mysore, Venkataram, Shashikumar, B
Format: Article
Language:English
Subjects:
Dermatology
Female
Humans
Light therapy
Low-Level Light Therapy - methods
Male
Phototherapy
Phototherapy - methods
Practice guidelines (Medicine)
Practice Guidelines as Topic
Prognosis
Prospective Studies
Psoriasis - diagnosis
Psoriasis - therapy
Randomized Controlled Trials as Topic
Retrospective Studies
Treatment Outcome
Ultraviolet Therapy - methods
Vitiligo - diagnosis
Vitiligo - therapy
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Summary:Background: Targeted phototherapy is a new form of phototherapy which has many advantages and disadvantages over conventional phototherapy. This article reviews the different technologies and outlines recommendations based on current evidence. Methods: A literature search was performed on targeted phototherapy to collect data. Relevant literature published till March 2014 was obtained from PubMed, EMBASE, and the Cochrane Library. Keywords like "targeted phototherapy", "excimer laser", "excimer lamp", "Nonchromatic ultraviolet light", "vitiligo", and "psoriasis", were used for literature search. All systematic reviews, meta-analysis, national guidelines, randomized controlled trials (RCT), prospective open label studies and retrospective case series in English were reviewed. Results: Three hundred and forty studies were evaluated, 24 of which fulfilled the criteria for inclusion in the guidelines. Conclusions and Recommendations: All forms of targeted phototherapy are useful in vitiligo. Good responses were seen in localized involvement, resistant lesions and in children in whom their use is more accepted and convenient (Level of evidence 2+, Grade of recommendation B). Similarly it is useful in psoriasis, either alone or in combination with drugs, even in resistant forms such as palmoplantar psoriasis. In view of expense and practical application, their use is limited to resistant lesions and localized disease. (Level of evidence 2+, Grade of recommendation B). But in other conditions there is no convincing evidence for its use. (Level of evidence 3+, Grade of recommendation C).
ISSN:0378-6323
0973-3922
1998-3611
DOI:10.4103/0378-6323.172902