Do X-linked diseases affect periodontal health?

Genetic factors play an important etiologic role in destructive periodontal diseases. There have been reports that sex chromosomes, especially disorders associated with the X chromosome, affect periodontal health. Although numerous X‐linked diseases have been reported to be associated with various p...

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Bibliographic Details
Published in:Periodontology 2000 2013-02, Vol.61 (1), p.266-278
Main Authors: Chien, Hua-Hong, Hart, Thomas C.
Format: Article
Language:English
Subjects:
Aggressive Periodontitis - genetics
Dentistry
Genes, X-Linked - genetics
Genes, Y-Linked - genetics
Genetic Diseases, X-Linked - genetics
Gingivitis - genetics
Humans
Periodontal Diseases - genetics
Periodontitis - genetics
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Summary:Genetic factors play an important etiologic role in destructive periodontal diseases. There have been reports that sex chromosomes, especially disorders associated with the X chromosome, affect periodontal health. Although numerous X‐linked diseases have been reported to be associated with various periodontal diseases, the association of gingivitis and/or periodontitis with these genetic syndromes should be considered tenuous and raises the question of whether the periodontal manifestation truly arises from an underlying X‐linked genetic etiology. A brief overview of genetics in relation to sex chromosomes and putative X‐linked genetic periodontal diseases is given.
ISSN:0906-6713
1600-0757
DOI:10.1111/j.1600-0757.2012.00441.x