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Perspectives on interventional diabetology: Duodenal exclusion is promising for human type 2 diabetes mellitus remission

Highlights • Type 2 diabetes mellitus (T2DM) is common in obese as well as nonobese patients. • Obese patients with T2DM undergoing bariatric surgery for weight loss show improved glycemic control. • Different bariatric surgeries for obese patients with T2DM have different outcomes in weight loss an...

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Published in:Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2016, Vol.32 (1), p.141-145
Main Authors: Ting, Ching-Heng, M.D., M.S, Syu, Yu-Fong, M.D, Chen, Liang-Yu, M.D, Lee, Fa-Yauh, M.D., F.A.C.G, Lee, Shou-Dong, M.D., A.G.A.F, Lee, Wei-Jei, M.D., Ph.D, Chen, Chih-Yen, M.D., Ph.D., A.G.A.F
Format: Article
Language:English
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Summary:Highlights • Type 2 diabetes mellitus (T2DM) is common in obese as well as nonobese patients. • Obese patients with T2DM undergoing bariatric surgery for weight loss show improved glycemic control. • Different bariatric surgeries for obese patients with T2DM have different outcomes in weight loss and remission rates of T2DM. • The effects of bariatric surgery in nonobese patients with T2DM on weight loss and glucose homeostasis continue to be investigated. • Other antiobesity interventions, such as endoscopic duodenal-jejunal bypass liner with a barrier effect from duodenal exclusion, prevent detrimental metabolic effects.
ISSN:0899-9007
1873-1244
DOI:10.1016/j.nut.2015.07.006