Incidence of Successful Pregnancy After Weight Loss Interventions in Infertile Women: a Systematic Review and Meta-Analysis of the Literature

Little is known about the impact of weight loss interventions on pregnancy rate. A systematic review with meta-analysis of literature has been performed to evaluate the incidence of successful pregnancy after bariatric interventions in infertile women. By pooling together data from 589 infertile obe...

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Bibliographic Details
Published in:Obesity surgery 2016-02, Vol.26 (2), p.443-451
Main Authors: Milone, Marco, De Placido, Giuseppe, Musella, Mario, Sosa Fernandez, Loredana Maria, Sosa Fernandez, Laura Virginia, Campana, Gabriele, Di Minno, Matteo Nicola Dario, Milone, Francesco
Format: Article
Language:English
Subjects:
Adult
Bariatric Surgery
Female
Fertility
Humans
Incidence
Infertility
Infertility, Female - etiology
Infertility, Female - surgery
Italy - epidemiology
Medicine
Medicine & Public Health
Meta-analysis
Obesity
Obesity - complications
Obesity - epidemiology
Obesity - surgery
Pregnancy - statistics & numerical data
Pregnancy Rate
Review Article
Surgery
Weight control
Weight Loss
Women
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Summary:Little is known about the impact of weight loss interventions on pregnancy rate. A systematic review with meta-analysis of literature has been performed to evaluate the incidence of successful pregnancy after bariatric interventions in infertile women. By pooling together data from 589 infertile obese women, we have been able to provide an aggregate estimation of successful pregnancy after weight loss interventions. Our results showed an impressive high incidence (58 %) of infertile women who become spontaneously pregnant after surgery. Based on our results, bariatric interventions could be included in the treatment of obesity-related infertility. However, the results must be interpreted with caution owning to the quality of the data provided by included studies. Further ad hoc studies are needed to validate the effectiveness of bariatric interventions on reproductive function.
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-015-1998-7