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Childhood adiposity: being male is a potential cardiovascular risk factor

As the earliest atherosclerotic lesions begin during childhood, our aim was to correlate gender-related adiposity to classical cardiovascular risk factors in a group of children.An observational and transversal analysis was carried out in a cohort consisting of 161 children of both sexes, aged 6 to...

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Bibliographic Details
Published in:European journal of pediatrics 2016-01, Vol.175 (1), p.63-69
Main Authors: Pires, António, Martins, Paula, Pereira, Ana Margarida, Marques, Margarida, Castela, Eduardo, Sena, Cristina, Seiça, Raquel
Format: Article
Language:English
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Summary:As the earliest atherosclerotic lesions begin during childhood, our aim was to correlate gender-related adiposity to classical cardiovascular risk factors in a group of children.An observational and transversal analysis was carried out in a cohort consisting of 161 children of both sexes, aged 6 to 17 years of age. Waist circumference was correlated to leptin, high-sensitivity C-reactive protein, systolic and diastolic blood pressure, plasma lipids, homeostasis model assessment-insulin resistance, and the left ventricular mass index. After adjusting for age, waist circumference in boys, compared to girls, correlated more strongly and directly to systolic ( r  = 0.538; p  
ISSN:0340-6199
1432-1076
DOI:10.1007/s00431-015-2599-0