Differential pathlength factor estimation for brain-like tissue from a single-layer Monte Carlo model

A Monte Carlo simulation-based computational model has been developed for tracing the pathway of light within a single layer of tissue like bloodless human brain. A reflectance mode source-detector geometry is assumed to illuminate the tissue slab with an irradiation of a near infrared wavelength an...

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Bibliographic Details
Published in:2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2015-01, Vol.2015, p.3279-3282
Main Authors: Chatterjee, Subhasri, Phillips, Justin P., Kyriacou, Panayiotis A.
Format: Article
Language:English
Subjects:
Computational modeling
Detectors
Monte Carlo methods
Optical detectors
Optical scattering
Photonics
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Summary:A Monte Carlo simulation-based computational model has been developed for tracing the pathway of light within a single layer of tissue like bloodless human brain. A reflectance mode source-detector geometry is assumed to illuminate the tissue slab with an irradiation of a near infrared wavelength and to detect the re-emitted light intensity. Light is considered to be attenuated within tissue by scattering and absorption. The model has been used to predict the relationship of mean optical path of photons with variable source-detector geometry and thus, to determine a differential pathlength factor (DPF) of 5.66 for incident light of wavelength 810 nm.
ISSN:1094-687X
1558-4615
2694-0604
DOI:10.1109/EMBC.2015.7319092