Resveratrol increases sirtuin 1 expression in peripheral blood mononuclear cells of premature infants and inhibits the oxidative stress induced by hyperoxia in vivo

To explore the effect of resveratrol on the levels of sirtuin 1 (SIRT1) and reactive oxygen species (ROS) in peripheral blood mononuclear cells (PBMCs) of premature infants exposed to hyperoxia. Peripheral blood and isolated PBMCs from premature infants (gestational age

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Bibliographic Details
Published in:Zhongguo dang dai er ke za zhi 2016-01, Vol.18 (1), p.72-77
Main Authors: Yang, Xi, Dong, Wen-Bin, Li, Qing-Ping, Kang, Lan, Lei, Xiao-Ping, Zhang, Lian-Yu, Lu, You-Ying, Zhai, Xue-Song
Format: Article
Language:Chinese
Subjects:
Female
Humans
Hyperoxia - metabolism
Infant, Newborn
Infant, Premature
Leukocytes, Mononuclear - metabolism
Lipid Peroxidation
Male
Oxidative Stress
Sirtuin 1 - blood
Stilbenes - pharmacology
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Summary:To explore the effect of resveratrol on the levels of sirtuin 1 (SIRT1) and reactive oxygen species (ROS) in peripheral blood mononuclear cells (PBMCs) of premature infants exposed to hyperoxia. Peripheral blood and isolated PBMCs from premature infants (gestational age
ISSN:1008-8830
DOI:10.7499/j.issn.1008-8830.2016.01.015