Factors associated with atypical femoral fracture

• Published in: Rheumatology international 2016-01, Vol.36 (1), p.65-71
• Main Authors: Kim, Dam, Sung, Yoon-Kyoung, Cho, Soo-Kyung, Han, Minkyung, Kim, Yee-Suk
• Format: Article
• Language: English
• Subjects: Age Factors; Aged; Aged, 80 and over; Diphosphonates - adverse effects; Female; Femoral Fractures - diagnostic imaging; Femoral Fractures - etiology; Humans; Medicine; Medicine & Public Health; Middle Aged; Original Article - Epidemiology of RMD; Proton Pump Inhibitors - adverse effects; Radiography; Retrospective Studies; Rheumatology
• ISSN: 0172-8172; 1437-160X
• DOI: 10.1007/s00296-015-3323-0

We aimed to investigate the proportion of atypical femoral fractures (AFF) among Korean femoral fracture patients and examined the factors associated with the development of AFF. Between 2003 and 2013, 607 female patients with low-energy femoral fractures who were hospitalized at a single university hospital were retrospectively enrolled in this study. Patients were classified into two groups according to the fracture site: Patients with subtrochanteric or diaphyseal femoral fractures were included in the AFF group, while patients with intertrochanteric or neck fractures were included in the typical femoral fracture (TFF) group. After comparing clinical and radiographic characteristics between groups, we used multivariable logistic regression analysis to explore risk factors for AFF. Thirty patients (4.9 %) with AFF and 577 patients (95.1 %) with TFF were identified. The AFF group was younger than the TFF group ( p