The Association among Feeding Mode, Growth, and Developmental Outcomes in Infants with Complex Congenital Heart Disease at 6 and 12 Months of Age

• Published in: The Journal of pediatrics 2016-02, Vol.169, p.154-159.e1
• Main Authors: Medoff-Cooper, Barbara, PhD, RN, FAAN, Irving, Sharon Y., PhD, RN, CRNP, FCCM, Hanlon, Alexandra L., PhD, Golfenshtein, Nadya, MS, RN, Radcliffe, Jerilynn, PhD, Stallings, Virginia A., MD, Marino, Bradley S., MD, Ravishankar, Chitra, MD
• Format: Article
• Language: English
• Subjects: Child Development; Feeding Methods - instrumentation; Female; Growth; Heart Defects, Congenital - complications; Heart Defects, Congenital - physiopathology; Humans; Infant; Male; Neurodevelopmental Disorders - etiology; Pediatrics; Prospective Studies
• ISSN: 0022-3476; 1097-6833
• DOI: 10.1016/j.jpeds.2015.10.017

Objective To assess the association between early anthropometric measurements, device-assisted feeding, and early neurodevelopment in infants with complex congenital heart diseases (CHDs). Study design Bayley Scales of Infant Development II were used to assess cognitive and motor skills in 72 infants with CHD at 6 and 12 months of age. Linear regression models were used to assess the association between mode of feeding and anthropometric measurements with neurodevelopment at 6 and 12 months of age. Results Of the 72 infants enrolled in the study, 34 (47%) had single-ventricle physiology. The mean Mental Developmental Index (MDI) and Psychomotor Developmental Index (PDI) scores at 6 months of age were 92 ± 10 and 81 ± 14, respectively. At 12 months of age, the mean MDI and PDI scores were 94 ± 12 and 80 ± 16, respectively. Lower length-for-age z score ( P