Using the Lower Limit of Normal Instead of the Conventional Cutoff Values to Define Predictors of Pulmonary Function Impairment in Subjects With Chronic Heart Failure

• Published in: Respiratory care 2016-02, Vol.61 (2), p.173-183
• Main Authors: Minasian, Armine G, van den Elshout, Frank J J, Dekhuijzen, P N Richard, Vos, Petra J E, Willems, Frank F, van den Bergh, Paul J P C, Heijdra, Yvonne F
• Format: Article
• Language: English
• Subjects: Aged; Airway Obstruction - diagnosis; Airway Obstruction - etiology; Analysis; Body Mass Index; Cardiac patients; Care and treatment; Complications and side effects; Cross-Sectional Studies; Female; Heart failure; Heart Failure - complications; Heart Failure - physiopathology; Humans; Lung diseases; Lung Diseases - diagnosis; Lung Diseases - etiology; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Reference Values; Respiratory Function Tests - standards; Respiratory Insufficiency - diagnosis; Respiratory Insufficiency - etiology; Risk Factors; Sex Factors; Smoking - adverse effects
• ISSN: 0020-1324; 1943-3654
• DOI: 10.4187/respcare.04101

Using the newer lower limit of normal criterion instead of the conventional cutoff values to define pulmonary function abnormalities may result in different predictors of pulmonary function impairment in patients with heart failure. Therefore, we assessed predictors of pulmonary function impairment in subjects with chronic heart failure according to the lower limit of normal in comparison with conventional cutoff values. In this prospective cross-sectional study, 164 chronic heart failure subjects (age 68 ± 10 y, 78% men, 88% New York Heart Association class I-II) with left ventricular ejection fraction