Effect of Statin Treatment and Low-Density Lipoprotein-Cholesterol on Short-Term Mortality in Acute Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention　– Multicenter Registry From Tokyo CCU Network Database

Background:Previous trials have found that low low-density lipoprotein-cholesterol (LDL-C) on admission was associated with increased mortality in patients with acute myocardial infarction (AMI). There are few reports, however, on the effect of low LDL-C with or without in-hospital statin treatment...

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Published in:Circulation Journal 2016/01/25, Vol.80(2), pp.461-468
Main Authors: Miura, Mizuki, Yamasaki, Masao, Uemura, Yukari, Yoshikawa, Masatomo, Miyauchi, Katsumi, Tanaka, Hiroyuki, Miyachi, Hideki, Yamashita, Jun, Suzuki, Makoto, Yamamoto, Takeshi, Nagao, Ken, Komuro, Issei, Takayama, Morimasa
Format: Article
Language:English
Subjects:
Acute myocardial infarction
Aged
Aged, 80 and over
Cholesterol, LDL - blood
Databases, Factual
Female
Hospital Mortality
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage
Lipid
Male
Middle Aged
Myocardial Infarction - blood
Myocardial Infarction - mortality
Myocardial Infarction - therapy
Percutaneous Coronary Intervention
Registries
Statin
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Summary:Background:Previous trials have found that low low-density lipoprotein-cholesterol (LDL-C) on admission was associated with increased mortality in patients with acute myocardial infarction (AMI). There are few reports, however, on the effect of low LDL-C with or without in-hospital statin treatment on short-term prognosis in AMI patients.Methods and Results:A total of 9,032 AMI patients underwent primary PCI in 68 centers in the Tokyo CCU Network Registry during 2009–2012, in whom LDL-C was measured in 6,486. We divided them into 4 groups: statin-treated/LDL-C
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-15-0889